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Comparative fracture risk amongst users of different anti-osteoporosis therapies: meta-analysis of propensity-matched cohort studies using data from the Clinical Practice Research Datalink (UK) and SIDIAP (Spain).

Abstract:
Despite the existence of plentiful evidence on the efficacy of anti-osteoporosis drugs (AOD) to prevent fractures in randomized controlled trials, there is a need for data on their comparative effectiveness and safety in actual practice. We aimed to compare the anti-fracture effectiveness of available AODs based on the observed risk of fracture while on treatment using ‘real world’ data from the UK NHS and Spanish healthcare records.
Publication status:
Published
Peer review status:
Reviewed (Other)
Version:
Accepted manuscript

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Publisher copy:
10.1093/rheumatology/kex061.011

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
ORCID:
0000-0002-7034-6168
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
ORCID:
0000-0003-3015-0432
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
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National Osteoporosis Society More from this funder
National Institute for Health Research More from this funder
Publisher:
Wiley Publisher's website
Publication date:
2017-04-21
Acceptance date:
2017-04-01
DOI:
ISSN:
1462-0324 and 1462-0332
Pubs id:
pubs:709982
URN:
uri:0fbe6e6b-f92a-4553-8f0f-281b37c1416f
UUID:
uuid:0fbe6e6b-f92a-4553-8f0f-281b37c1416f
Local pid:
pubs:709982

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