Journal article
Efficacy and safety of statin therapy in older people: meta-analysis of individual participant data from 28 randomised controlled trials
- Abstract:
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Background: Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We undertook a meta-analysis of data from all large statin trials to compare the effects of statin therapy at different ages.
Methods: In this meta-analysis, randomised trials of statin therapy were eligible if they aimed to recruit at least 1000 participants with a scheduled treatm...
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- Publication status:
- Published
- Peer review status:
- Peer revivewed
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- Files:
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(Version of record, pdf, 653.4KB)
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- Publisher copy:
- 10.1016/S0140-6736(18)31942-1
Authors
Funding
Cancer Research UK
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British Heart Foundation
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Medical Research Council
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National Heart Foundation
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Clinical Trial Service Unit and Epidemiological Studies Unit
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Journal website
- Volume:
- 393
- Issue:
- 10170
- Pages:
- 407-415
- Publication date:
- 2019-02-02
- Acceptance date:
- 2018-08-14
- DOI:
- EISSN:
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1474-547X
- ISSN:
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0140-6736
Item Description
- Pubs id:
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pubs:921953
- UUID:
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uuid:0db1241b-e731-4aaf-9f3e-ab3596ebb670
- Local pid:
- pubs:921953
- Source identifiers:
-
921953
- Deposit date:
- 2018-09-26
Terms of use
- Copyright holder:
- Crown Copyright
- Copyright date:
- 2019
- Notes:
- Crown Copyright © 2018 Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license
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