Journal article
Changes in natural killer cells and exhausted memory regulatory T Cells with corticosteroid therapy in acute autoimmune hepatitis
- Abstract:
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Autoimmune hepatitis (AIH) is an immune-mediated liver disease currently treated by immunosuppressive medications with significant side effects. Thus, novel mechanistic treatments are greatly needed. We performed prospective deep immunophenotyping of blood immune cells in patients with acute AIH before and after corticosteroid therapy. Blood samples from 26 patients with acute AIH (United Kingdom-AIH Consortium) were phenotyped by flow cytometry at baseline and 4 months after starting cortico...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.2MB)
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- Publisher copy:
- 10.1002/hep4.1163
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Authors
Funding
+ United Kingdom Autoimmune Hepatitis Translational Research Collaboration
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Hepatology Communications Journal website
- Volume:
- 2
- Issue:
- 4
- Pages:
- 421-436
- Publication date:
- 2018-02-26
- Acceptance date:
- 2018-01-22
- DOI:
- EISSN:
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2471-254X
- Pmid:
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29619420
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:834050
- UUID:
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uuid:0daa33fc-8ee5-48d5-8a84-e03fa1a0e86d
- Local pid:
- pubs:834050
- Deposit date:
- 2018-04-07
Terms of use
- Copyright holder:
- Klenerman et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases. This is an open access article under the terms of the Creative Commons Attribution License, which permits use and distribution in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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