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Journal article

Changes in natural killer cells and exhausted memory regulatory T Cells with corticosteroid therapy in acute autoimmune hepatitis

Abstract:

Autoimmune hepatitis (AIH) is an immune-mediated liver disease currently treated by immunosuppressive medications with significant side effects. Thus, novel mechanistic treatments are greatly needed. We performed prospective deep immunophenotyping of blood immune cells in patients with acute AIH before and after corticosteroid therapy. Blood samples from 26 patients with acute AIH (United Kingdom-AIH Consortium) were phenotyped by flow cytometry at baseline and 4 months after starting cortico...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/hep4.1163

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Publisher:
Wiley Publisher's website
Journal:
Hepatology Communications Journal website
Volume:
2
Issue:
4
Pages:
421-436
Publication date:
2018-02-26
Acceptance date:
2018-01-22
DOI:
EISSN:
2471-254X
Pmid:
29619420
Language:
English
Keywords:
Pubs id:
pubs:834050
UUID:
uuid:0daa33fc-8ee5-48d5-8a84-e03fa1a0e86d
Local pid:
pubs:834050
Deposit date:
2018-04-07

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