Thesis icon

Thesis

Investigating the mechanisms underlying myocardial regeneration in the Mexican cavefish

Abstract:

Following myocardial infarction (MI), the adult human heart is unable to regenerate and replace the lost cardiac muscle with new functioning cardiomyocytes. Instead, it forms a permanent non-contractile scar that impairs cardiac function, which may later result in heart failure. In contrast, the adult zebrafish and neonatal mouse heart possess an innate ability to regenerate their heart after injury, with studies revealing myocardial proliferation in the border zone next to the injury site...

Expand abstract

Actions


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Sub department:
Physiology Anatomy & Genetics
Research group:
Mommersteeg group
Oxford college:
Wolfson College
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Sub department:
Physiology Anatomy & Genetics
Oxford college:
St Cross College
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Sub department:
Physiology Anatomy & Genetics
Oxford college:
Jesus College
Role:
Supervisor
ORCID:
0000-0002-9862-7332
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2022-08-13

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP