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ThymosinB4- A novel regulator of Low density lipoprotein receptor related protein 1(LRP1) in vascular disease

Abstract:

Cardiovascular diseases, including atherosclerosis and abdominal aortic aneurysm (AAA), are amongst the foremost causes of global morbidity. Despite decades of research, the mechanisms underlying disease progression remain unresolved, resulting in a lack of efficient pharmacological therapies to prevent disease progression. Maintaining vascular stability is fundamental to protect against disease pathogenesis. Contractile smooth muscle cells (VSMCs) and elastin-rich extracellular matrix (EC...

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Oxford college:
Wolfson College
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Oxford college:
Wolfson College
Role:
Supervisor
More from this funder
Programme:
MRC Doctoral Training Partnership
Funding agency for:
Smart, N
Munshaw, S
Grant:
BRT00030
MR/N013468/1
MR/K501256/1
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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