Journal article
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.
- Abstract:
-
Epithelial ovarian cancer has a major heritable component, but the known susceptibility genes explain less than half the excess familial risk. We performed a genome-wide association study (GWAS) to identify common ovarian cancer susceptibility alleles. We evaluated 507,094 SNPs genotyped in 1,817 cases and 2,353 controls from the UK and approximately 2 million imputed SNPs. We genotyped the 22,790 top ranked SNPs in 4,274 cases and 4,809 controls of European ancestry from Europe, USA and Aust...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/ng.424
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Authors
Bibliographic Details
- Journal:
- Nature genetics
- Volume:
- 41
- Issue:
- 9
- Pages:
- 996-1000
- Publication date:
- 2009-09-05
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- URN:
-
uuid:09f64783-3edc-40d8-afe7-2fbc5ea88fa4
- Source identifiers:
-
41343
- Local pid:
- pubs:41343
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2009
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