Journal article
High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine.
- Abstract:
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Background
Neisseria meningitidis is a globally important cause of meningitis and septicaemia. Twelve capsular groups of meningococci are known, and quadrivalent vaccines against four of these (A, C, W and Y) are available as plain-polysaccharide and protein-polysaccharide conjugate vaccines. Here we apply contemporary methods to describe B-cell responses to meningococcal polysaccharide and conjugate vaccines.
Methods
Twenty adults were randomly assigned to receiv...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
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(Version of record, pdf, 1.8MB)
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- Publisher copy:
- 10.1186/s13073-017-0400-x
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Authors
Funding
+ Jenner Institute
More from this funder
Funding agency for:
Pollard, A
Grant:
James Martin Senior Fellow
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Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Genome Medicine Journal website
- Volume:
- 9
- Issue:
- 1
- Pages:
- 11
- Publication date:
- 2017-01-01
- Acceptance date:
- 2017-01-05
- DOI:
- ISSN:
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1756-994X
- Source identifiers:
-
675167
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:675167
- UUID:
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uuid:070022b5-4ccc-4764-98ee-a944bc66010a
- Local pid:
- pubs:675167
- Deposit date:
- 2017-02-07
Terms of use
- Copyright holder:
- Pollard et al
- Copyright date:
- 2017
- Notes:
- © The Author(s). 2017 This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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