Book section : Chapter
Biological therapies for asthma
- Abstract:
-
Five to 10% of asthma patients remain symptomatic and/or have asthma attacks despite adequate inhaled and systemic therapy. Eosinophilic, type 2 airway inflammation is seen in half of these patients with severe asthma. There is now convincing evidence that type 2 inflammation drives susceptibility to asthma attacks and is associated with a good response to biological therapies. Monoclonal antibodies targeting immunoglobulin E, interleukin (IL)-5 and IL-4/13 now have established efficacy in se...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Host title:
- Encyclopedia of Respiratory Medicine
- Pages:
- 411-434
- Publication date:
- 2021-09-17
- DOI:
- ISBN:
- 978-0-08-102724-0
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Chapter
- Pubs id:
-
1185472
- Local pid:
- pubs:1185472
- Deposit date:
- 2021-07-09
Terms of use
- Copyright holder:
- Elsevier.
- Copyright date:
- 2021
- Rights statement:
- © 2022 Elsevier Ltd. All rights reserved
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