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INDIANA: An in-cell diffusion method to characterize the size, abundance and permeability of cells

Abstract:

NMR and MRI diffusion experiments contain information describing the shape, size, abundance, and membrane permeability of cells although extracting this information can be challenging. Here we present the INDIANA (IN-cell DIffusion ANAlysis) method to simultaneously and non-invasively measure cell abundance, effective radius, permeability and intrinsic relaxation rates and diffusion coefficients within the inter- and intra- cellular populations. The method couples an experimental dataset comp...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jmr.2018.12.001

Authors


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Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
Keble College
Role:
Author
ORCID:
0000-0002-8072-5911
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Oxford college:
Keble College
Role:
Author
Expand authors...
Publisher:
Elsevier Publisher's website
Journal:
Journal of Magnetic Resonance Journal website
Volume:
302
Pages:
1-13
Publication date:
2019-01-06
Acceptance date:
2018-12-03
DOI:
EISSN:
1096-0856
ISSN:
1090-7807
Source identifiers:
965608
Language:
English
Pubs id:
pubs:965608
UUID:
uuid:057a2513-3457-40a5-989e-0908bd917319
Local pid:
pubs:965608
Deposit date:
2019-01-22

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