Journal article
An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a
- Abstract:
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The microRNA-34a is a well-studied tumor suppressor microRNA (miRNA) and a direct downstream target of TP53 with roles in several pathways associated with oncogenesis, such as proliferation, cellular growth, and differentiation. Due to its broad tumor suppressive activity, it is not surprising that miR34a expression is altered in a wide variety of solid tumors and hematological malignancies. However, the mechanisms by which miR34a is regulated in these cancers is largely unknown. In this stud...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.7MB)
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- Publisher copy:
- 10.1038/s41419-018-0777-5
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Authors
Funding
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Cell Death and Disease Journal website
- Volume:
- 9
- Issue:
- 7
- Article number:
- 736
- Publication date:
- 2018-07-03
- Acceptance date:
- 2018-05-31
- DOI:
- ISSN:
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2041-4889
- Pmid:
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29970884
- Source identifiers:
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892749
Item Description
- Language:
- English
- Pubs id:
-
pubs:892749
- UUID:
-
uuid:025ca355-bec3-48c3-ab19-341f2352effa
- Local pid:
- pubs:892749
- Deposit date:
- 2018-08-07
Terms of use
- Copyright holder:
- Serviss et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 The Authors. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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