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Thesis

Plasmodium falciparum population genetics in northern Ghana

Abstract:

The main thrust of this thesis was to characterize P.falciparum genetic diversity in northern Ghana. To do this, I used simple techniques to purify P. falciparum DNA from clinical samples across a rural setting for whole-genome sequencing. The goal was to provide a framework for exploring host-parasite genetic interactions. Utilizing Illumina deep sequencing data for 277 isolates I analyzed P. falciparum genetic diversity and described within-host diversity across this area.

I obser...

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  • (Dissemination version, pdf, 3.3MB)

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Institution:
University of Oxford
Division:
MSD
Oxford college:
Wolfson College
Role:
Author

Contributors

Division:
MSD
Role:
Supervisor
Division:
MSD
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:023a6b97-5a30-4a66-bcad-0d85271062fd
Local pid:
ora:7337
Deposit date:
2013-09-20

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