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1

Thesis

Structural studies of interactions between three human pathogens and their host

Gérard, SF
2022

2

Thesis

Structural studies of the neutrophil cell surface receptors GPR97 and CD177 and their interaction with PR3

Zheng-Gérard, C
2022

3

Thesis

Structural and functional characterisation of the fungal plasma membrane proton pump, Pma1, and related P-Type ATPases

Geurts, MMG
2022

4

Thesis

Engineering a modular virus-like particle platform for enhanced vaccine assembly

Wu, H-J
2022

5

Thesis

Host gene expression change during viral stress

Brophy, C
2022

6

Thesis

Structural and functional studies with native mass spectrometry — insights into membranes and glycoproteins

Chen, S
2022

7

Thesis

Structural and biochemical characterisation of human integral membrane proteins regarded as potential therapeutic targets

da Costa Cabral Gomes Páscoa, T
2022

8

Thesis

Investigating the non-protein binding targets of the Teneurin extracellular domain and their biological significance

Crowther, O
2022

9

Thesis

Investigating the role of lipids and small-molecule ligands in hedgehog signalling using molecular dynamics simulations

Ansell, T
2022

10

Thesis

Investigating the communication of mismatch recognition and strand incision in the DNA mismatch repair pathway

Banaz, N
2022

11

Thesis

Biological applications of chemically modified recombinant histones

Josephson, B
2022

12

Thesis

Hedgehog Acyltransferase: Structure, Function and Inhibition

Coupland, C
2022

13

Thesis

Development of a clean and simple biocatalysed flavin regeneration system to aid sustainable chemical synthesis

Joseph Srinivasan, S
2022

14

Thesis

Identification of a novel role for PARPs in replication stress recovery

Richards, F
2022

15

Thesis

Adapting nanobody scaffolds as protein chaperones for effective crystallization and good protein behaviour in cryo-EM

Ye, M
2021

16

Dataset

Raw data for "Hundt et al., Direct observation of the molecular mechnism underlying protein polymerization, Science Advances 2022"

Hundt, N, Cole, D, Hantke, M F, et al.
2022

17

Thesis

Identification of novel players implicated in replication-dependent and independent DNA interstrand crosslink (ICL) repair

Yaprianto, K
2021

18

Thesis

The selective partitioning of mRNA in biomolecular condensates

Hickling, M
2022

19

Thesis

Structural analysis of Wnt signalling pathways

Ruza, RR
2021

20

Thesis

Mechanistic studies of DNA repair and genome instability

Nathan, WJ
2021

21

Thesis

Molecular dynamics simulations of membrane proteins in nanodiscs with investigation of protein-lipid interactions

Horrell, M
2022

22

Thesis

An interdisciplinary approach for developing novel methods to study silks

Oh, YJ
2021

23

Thesis

Molecular simulations of ion channel gating

Pipatpolkai, T
2021

24

Thesis

Protein folding and structure prediction: biological and physical perspectives

Chonofsky, MA
2020

25

Thesis

Characterisation of the influenza virus matrix protein M1 and its role in oligomerisation

Mohd Kipli, MFH
2020

26

Thesis

Investigating the epigenetic regulation of the eukaryotic centromere by the segregase enzyme p97

East, S
2021

27

Thesis

Spatially resolved proteomics of a human brain tumour

Davis, S
2021

28

Thesis

Characterisation of oxygen regulation mechanisms in Rhizobium leguminosarum for repurposing as tools in the engineering of nitrogen fixation

Rutten, PJ
2021

29

Thesis

Quantifying redox metabolism in the plant metabolic network

Smith, E
2021

30

Thesis

Actin regulation in activity-dependent synaptic plasticity at the Drosophila neuromuscular junction

Gu, Y
2022

31

Thesis

Structural studies on oligosaccharide transport and sugar scavenging in bacteria

Lee, MO
2021

32

Thesis

The organisation and dynamics of Escherichia coli outer membrane proteins

Inns, P
2021

33

Thesis

Signal transduction of the GPCR Smoothened: a key protein in Hedgehog-regulated morphogenesis and oncogenesis

Woolley, R
2021

34

Thesis

Investigating the dynamics of KDEL receptor signalling

Spoendlin, F
2022

35

Thesis

Protein modulation of ion channels

Cloake, AM
2021

36

Thesis

Establishing an antibody mimetic applicable to targeting in the gastrointestinal tract

Wicke, NS
2021

37

Thesis

Metabolic flux analysis in Euglena gracilis

Inwongwan, S
2020

38

Thesis

Mechanisms of TonB-dependent protein import in Pseudomonas aeruginosa

Goult, J
2021

39

Thesis

Structural & biophysical characterisation of M. tuberculosis MmpL3

Adams, O
2021

40

Thesis

Investigating the function and regulation of cohesin ATPase

Voulgaris, M
2021

41

Thesis

Towards understanding of unconventional kinetochores in kinetoplastids

Ludzia, P
2021

42

Thesis

The linear ubiquitin assembly complex’s recruitment to signaling complexes: The role of HOIP’s zinc finger domains

Nathanail, E
2021

43

Thesis

Genomic single molecule analysis of chromatin structure around DNA replication origins in Saccharomyces cerevisiae

Jeffery, HM
2021

44

Thesis

Studying protein interaction and glycosylation with chemical proteomics

Nadal, S
2020

45

Thesis

Studying the function and regulation of non-coding transcription in fission yeast by the exosome complex

Shah, S
2014

46

Thesis

Structural and functional characterisation of the group II chaperonin CCT/TRiC

Kelly, J
2020

47

Thesis

Target search mode of a disordered transcription factor

Kelly, C
2021

48

Thesis

Towards defining mechanisms involved in β-lactam resistance using serial crystallography

Lucic, A
2021

49

Thesis

Cellular target engagement and selectivity profiling of small molecules for mechanism-of-action studies

Stefaniak, J
2019

50

Thesis

Functional analysis of cancer/testis antigens in human cancer

Pagotto, A
2013

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