A RANDOMIZED BLINDED COMPARISON OF 2 DOSES OF ANTIVENOM IN THE TREATMENT OF BOTHROPS ENVENOMING IN SAO-PAULO, BRAZIL
|Author||JORGE, M; CARDOSO, J; CASTRO, S; et al|
|Key phrase||SNAKE BITE BOTHROPS ANTIVENOM BRAZIL|
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.
|Abstract||To identify susceptibility loci for visceral leishmaniasis, we undertook genome-wide association studies in two populations: 989 cases and 1,089 controls from India and 357 cases in 308 Brazilian families (1,970 individuals). The HLA-DRB1-HLA-DQA1 locus was the only region to show strong evidence of association in both populations. Replication at this region was undertaken in a second Indian population comprising 941 cases and 990 controls, and c ... [truncated at 450 characters in length]|
|Author||LeishGEN Consortium; Wellcome Trust Case Control Consortium 2; Fakiola, M; et al|
|Key phrase||Brazil Electrophoresis, Agar Gel Gene Frequency Genetic Predisposition to Disease Genome-Wide Association Study Genotype HLA-DQ alpha-Chains HLA-DRB1 Chains Haplotypes Humans India Leishmaniasis, Visceral Linear Models Odds Ratio Oligonucleotide Array Sequence Analysis Polymorphism, Single Nucleotide|
Yellow fever virus maintenance in Trinidad and its dispersal throughout the Americas.
|Abstract||Trinidad, like many other American regions, experiences repeated epizootics of yellow fever virus (YFV). However, it is unclear whether these result from in situ evolution (enzootic maintenance) or regular reintroduction of YFV from the South American mainland. To discriminate between these hypotheses, we carried out a Bayesian phylogeographic analysis of over 100 prM/E gene sequences sampled from 8 South American countries. These included newly ... [truncated at 450 characters in length]|
|Author||Auguste, AJ; Lemey, P; Pybus, OG; et al|
|Key phrase||Alouatta Animals Base Sequence Bayes Theorem Brazil DNA Primers DNA, Viral Genes, Viral Humans Models, Biological Molecular Epidemiology Molecular Sequence Data Phylogeny South America Time Factors Trinidad and Tobago Viral Envelope Proteins Viral Matrix Proteins Yellow Fever Yellow fever virus|
Representative sampling and analysis in HIV molecular epidemiology studies.
|Author||Hemelaar, J; Gouws, E; Ghys, PD; et al|
|Key phrase||Brazil Genetic Variation HIV HIV Infections Humans Molecular Epidemiology Sampling Studies|
Crotaline snake bite in the Ecuadorian Amazon: randomised double blind comparative trial of three South American polyspecific antivenoms.
|Abstract||To compare the efficacy and safety of three polyspecific antivenoms for bites by pit vipers.|
|Author||Smalligan, R; Cole, J; Brito, N; et al|
|Key phrase||Adolescent Adult Aged Aged, 80 and over Animals Antivenins Brazil Child Child, Preschool Colombia Crotalid Venoms Crotalus Double-Blind Method Ecuador Female Humans Male Middle Aged Snake Bites Treatment Outcome|