Chronic otitis media (OM) is an archetypal complex disease, which is particularly prevalent in childhood. Epidemiological data suggest high heritability for disease susceptibility, but previous genetic association studies have had methodological flaws, and none have specifically focused on chronic OM phenotypes.
Mouse models represent one way to ascertain candidate loci for human association testing. A number of mouse models of middle e ... [truncated at 450 characters in length]
|Creator||Mahmood F Bhutta;|
|Subject||Genetics (life sciences) Genetics (medical sciences) Infectious diseases Otolaryngology|
|Abstract||It has been suggested that specific reading disability (SRD) may be attributable to an impaired ability to perceive spectral differences between sounds that leads to a deficit in frequency discrimination and subsequent problems with language and literacy. The objective of the present study was threefold. We aimed to (a) determine whether children with mild to moderate sensorineural hearing loss were impaired in their ability to discriminate frequ ... [truncated at 450 characters in length]|
|Author||L. F. Hallyday; D. V. M. Bishop;|
|Subject||Otolaryngology Experimental psychology Language and cognitive development|