This thesis is concerned with the use of kinetic resolution strategies for the preparation of enantiomerically pure materials.
Chapter 1 introduces kinetic resolution. The limitations of conventional kinetic resolutions are described and the methods used to overcome these limitations are discussed.
Chapter 2 presents a double kinetic resolution strategy where the recovered reactant from the first kinetic resolution is used as st ... [truncated at 450 characters in length]
|Author||De Sousa, J. A. A.;|
|Subject||Diastereoisomers Synthesis Chirality Amino acids Separation Esters|
A number of organometallic transformations related to proposed elementary steps in the reductive polymerization of carbon monoxide are discussed.
The use of isonitrile as model ligands for carbon monoxide, with which they are isoelectronic, is proposed. Investigations show that alkyl migration to isonitrile is preferred over migration to carbon monoxide. Iminoformyl products due to hydride migration to isonitrile are not,,however, obse ... [truncated at 450 characters in length]
|Author||Brown, Stephen L.;|
|Subject||Organometallic chemistry Stereochemistry Ligands Chirality Carbon monoxide Polymerization Isocyanides|
This thesis describes the applications to asymmetric synthesis of the highly diastereoselective carbon-carbon bond forming reactions of α,β-unsaturated acyl ligands bound to the chiral iron auxiliary [(η5-C5H5)Fe(CO)(PPh3)].
Chapter 1 briefly reviews the use of chiral auxiliaries in asymmetric synthesis.
Chapter 2 discusses the conformation of [(η5-C5H5)F ... [truncated at 450 characters in length]
|Author||Walker, J. C. (Jonathan Charles);|
|Subject||Asymmetric synthesis Iron compounds Acyl halides Chirality Stereochemistry|