Discussion of The Forward Search: Theory and Data Analysis by Anthony C. Atkinson, Marco Riani, and Andrea Ceroli.
|Abstract||The Forward Search Algorithm is a statistical algorithm for obtaining robust estimators of regression coefficients in the presence of outliers. The algorithm selects a succession of subsets of observations from which the parameters are estimated. The present note shows how the theory of empirical processes can contribute to the understanding of how the subsets are chosen and how the sequence of estimators is changing.|
|Creator||Søren Johansen; Bent Nielsen;|
Experimental dissidence: economies of credibility in drug regulation
|Abstract||In 2004, a former FDA medical officer named David Ross watched news coverage of one of the highest-profile pharmaceutical controversies in recent years: Merck’s withdrawal of Vioxx, its bestselling painkiller, from the global marketplace. At the time, David Ross railed to his wife about the actions of David Graham, an associate director of drug safety at the FDA who drew international attention for testifying before the US Senate about the FDA’s ... [truncated at 450 characters in length]|